Wednesday, June 1, 2011

Treatment of Clostridium Difficile Diarrhea

Clostridium difficile infection usually occurs after prolonged antibiotic use or acquired from hospital through cross infection.
 Scanning electron micrograph of Clostridium di...Scanning Microscope Image of C. difficile
Prolonged especially broad spectrum antibiotic use kills the natural beneficial gut microbes called gut flora. That helps the pathologic bacteria like clostridium to colonize. That may cause diarrhea, called pseudo membranous enterocolitis, which is resistant to common antibiotics used in infective diarrheas.
At present, it is treated by;
· Stopping the antibiotics.
· Adding gut friendly bacteria like lactobacilli.
· Adding Metronidazole.
· Adding Vancomycin.
· Supportive treatment in form of fluid management.
With these treatments the relapse is seen many a times.
Now, a new drug, Fidaxomicin has been approved by FDA to treat this diarrhea; which said to have superior results than the existing treatment. The relapse rate is said to be lower.
Enhanced by Zemanta


Get my updates delivered into your inbox; Privacy Policy :

Click here to Subscribe news feed from "Clinicianonnet; so that you do not miss out anything that can be valuable to you !!


Related Posts Plugin for WordPress, Blogger...