Friday, September 2, 2011

Co-prescription of Pain Killers and PPI may Spare Stomach and Hurt Intestine

Popularly known as pain killers, are a class of drugs called non-steroidal anti-inflammatory and analgesic drugs (NSAIDs). Come within the drugs are ibuprofen, diclofenac and nimesulide etc.
Most of the times physicians prescribe acid suppressing drugs amongst which popular is a group of drugs known as proton pump inhibitors (PPIs). These include omeprazole and rabeprazole etc..
Stomach diagram in Inkscape.Image via Wikipedia
The PPIs very effectively suppress acid secretion in the stomach and are protective to the damaging effect of NSAIDs to a larger extent. Those prevent gastritis and ulceration in stomach and duodenum.
Now, it has been seen that co-prescription of PPIs with the NSAIDs may spare the stomach and cause damage to the intestine.
Still the use of analgesics is to continue, but a judicious use and no abuse is perhaps the answer. Besides this more research in formulating the drugs may be needed.   
Enhanced by Zemanta


Get my updates delivered into your inbox; Privacy Policy :

Click here to Subscribe news feed from "Clinicianonnet; so that you do not miss out anything that can be valuable to you !!


Related Posts Plugin for WordPress, Blogger...