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Some times this maneuver becomes difficult and may sometimes damage the blood vessels. Now they can temporarily seal a blood vessel less than 4 mm diameter, except that supplying to the brain with a chemical LeGoo.
The US Food and Drug Administration has approved LeGoo gel to temporarily stop blood flow during vascular and cardiovascular surgery without using clamps or elastic loops.
LeGoo is a water-soluble and temperature-sensitive gel; and is liquid at room temperature. When injected into a blood vessel, LeGoo forms a gel plug that molds to the shape of the blood vessel and stops blood flow for up to 15 minutes, the FDA notes in a statement.
Repair of the vessel by Suturing can be performed directly through the gel. After completion of the procedure, it is dissolved by applying ice directly to the vessel. The diluted material will not re-gel once it is dissolved: and passes through the micro-circulation to be excreted in urine.
According to Christy Foreman, the director of the Office of Device Evaluation in the FDA's Center for Devices and Radiological Health, LeGoo is "an innovative device that offers surgeons an additional aid during vascular surgery. The gel's unique properties may facilitate surgeries that entail the joining or grafting blood vessels."
Studies have shown that LeGoo is "biocompatible and non-toxic," the FDA notes. Data from a clinical trial of 110 patients who underwent off-pump coronary artery bypass surgery showed the compound to be "as safe and effective as vessel loops," the FDA says.
LeGoo is approved for temporary stoppage of blood flow in blood vessels below the neck that are 4 mm or smaller in diameter. It is contraindicated for use on vessels supplying blood to the brain.